The gastrointestinal (GI) tract is a finely balanced environment where 300 different strains of bacteria compete for space and nutrients. When there is a healthy balance (eubiosis), few symptoms exist. However, dysbiosis can occur when an overabundance of potentially harmful organisms prevail. The natural flora balance can be upset by medications (antibiotics, oral contraceptives, etc.), drinking chlorinated water, or eating too many processed foods. Probiotics have been extensively studied for their effect on the GI environment, and are characterized as having broad health benefits including increasing populations of healthy bacteria following microflora imbalance and increasing detoxification of harmful compounds.
Because probiotics are live organisms, there are many challenges associated with manufacturing and distributing probiotic supplements. For a probiotic to be effective, it must be shelf-stable through the expiration date and precisely delivered to the GI tract where it can have maximum benefit. The microorganisms in Ortho Biotic are first protected, sealed, and freeze dried away from moisture, heat, light and oxygen. This puts the bacteria into a state of “hibernation,” allowing them to remain dormant until they are exposed to moisture in the GI tract. By utilizing advanced encapsulation technology, the probiotic organisms are preserved and then released on target for maximum benefit.
Ortho Biotic is a unique probiotic formula designed to deliver active organisms that have been shown to promote healthy gut flora, protect intestinal integrity and boost immune function. Each capsule includes seven proven probiotic strains chosen for their ability to withstand the harsh GI environment and adhere to the intestinal tract. Also included is Saccharomyces boulardii, an extensively researched microorganism shown to help restore microflora balance by enhancing “resident” probiotics.
1 scoop (1.7 g) per day or as recommended by your health care professional.
Lactobacillus acidophilus is a beneficial bacterial strain that is normally found in the human intestinal tract and mouth and is commercially used in dairy products for the production of acidophilus-type yogurt. L. acidophilus ferments various carbohydrates producing lactic acid, a short chain fatty acid that increases the absorption and bioavailability of minerals. This includes calcium, copper, magnesium and manganese. The L. acidophilus La-14 strain has been specifically chosen for Ortho Biotic because of its strong adherence and survivability. It has been demonstrated to tolerate exposure to stomach acid, bile salts and antibiotics, including Ciproflaxin, Polymyxin B and Tetracycline.
Lactobacillus paracasei is a lactic acid secreting strain that has been shown to protect against the harmful effects of bacteria such as Staphylococcus aureus. Lactobacillus paracasei colonizes the intestinal tract first then reinforces defense mechanisms by supporting immune system response.
Bifidobacterium bifidum is predominantly found in the colon. Bifidobacterium is a normal resident of healthy infant GI tracts and usually colonizes within four days of life. B. bifidumhas been shown to effectively compete with harmful bacteria such E. coli Staphyolococcus aureus and Camplylobacter jejuni. This suggests that B. bifidum’s lactic acid and acetic acid production provides an antagonistic action against pathogens to help maintain microflora balance.
Bifidobacteria lactis is predominantly found in the colon. A double-blind, randomized, placebo-controlled trial on subjects receiving B. lactisor placebo for eight weeks found that B. lactis supported a balanced immune response in individuals hypersensitive to environmental allergens. Studies examining immune development and dietary supplementation with B. lactis have shown that it supports GI health by reducing intestinal permeability.
Lactobacillus plantarum is a beneficial bacteria commonly found in fermented foods, including sauerkraut, pickles, brined olives and sourdough. L. plantarum has been found to compete against strains of Clostridium difficile and Clostridium perfringens, due to the production of bacteriocins (lethal proteins) that inhibit bacterial growth. Studies have also demonstrated that L. plantarum helps boost the immune response by stimulating Th1-mediated immunity.
Lactobacillus rhamnosus has been found to be beneficial in the expelling of parasites. In a study examining exposure to the parasite Trichuris muris, L. rhamnosus significantly enhanced worm expulsion. It has also been shown to promote GI health by increasing intestinal cell replication.
Saccharomyces boulardii is a probiotic yeast that was first isolated from the skin of the tropical fruits lychee and mangosteen in 1923. S. boulardii plays a role in supporting immune defense by increasing levels of the crucial antibody, secretory IgA, and creating a first line of defense that helps bind and clear harmful bacteria.