Your New Probiotic for SIBO

stomach pain

A Dual Action Solution for SIBO

The functional medicine spotlight is on SIBO, and for a good reason: SIBO is difficult to pinpoint, complex in nature, and many patients have it and do not realize it.

You have seen this patient type before: gas, bloating, and intolerance to certain foods (even healthy ones) and probiotics. Many gastrointestinal complaints are attributed to sensitivity, but the culprit may be an imbalance in the ecosystem of the small intestine.

Ortho Spore IG™

Ortho Spore IG product image

Ortho Spore IG™ is a spore-based, broad-spectrum probiotic formula designed to promote a healthy gut microflora, protect mucosal integrity, and relieve small intestinal bacterial overgrowth (SIBO). Uniquely included in this formula are serum-derived bovine immunoglobulins that bind to and eliminate microbes and toxins that are common in SIBO.

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A Dual-Action Solution for SIBO Patients


Microbial diversity without disruption

Activated Bacillus strains use quorum sensing in the small intestine to gently "push" non-resident species back into the large intestine and restore proper microbial diversity and balance.


Increase mucosal immunity and bind harmful toxins

Serum-derived bovine immunoglobulins (SBI) bind and “pull” the remaining lipopolysaccharides (LPS), gram-negative bacterial cell components, and other toxins from the environment for elimination.


    Quorum Sensing

Three novel Bacillus strains to gently rebalance gut health

Bacillus spores are a novel probiotic that remain dormant until they reach the small intestine. This allows Bacillus spores to be gentler in the GI tract than other probiotics. Within the small intestine, they spring into action, ready to detect and push out unwanted bacteria using quorum sensing. They produce compounds that repel and break down these unwelcome organisms.

Ortho Spore IG™ delivers three Bacillus strains, all with proven ability to support gut health in SIBO patients.

  • Bacillus coagulans
  • Bacillus clausii
  • Bacillus subtilis

The Immunoglobulin Advantage

Bacillus strains are a powerful force for combatting SIBO, but they need an ally to be most effective. Serum-derived bovine immunoglobulins gently bind and eliminate lipopolysaccharides and other unwanted toxins.

The dairy-free immunoglobulins in Ortho Spore IG™ work with Bacillus strains to deliver a dual-action solution for SIBO patients. We formulate using a high-concentration dose (1 g) for an optimal, yet well-tolerated, benefit.


Immunoglobulin Protection

Targeted probiotic supplements

that support a variety of nutrition protocols

Ortho Biotic® is a unique probiotic formula designed to deliver active organisms shown to promote healthy gut microflora, protect intestinal integrity and boost immune function.

Ortho Biotic® 100 is a high-dose probiotic that delivers 100 billion active cultures for cases of gastrointestinal and immune distress.

Probiotic 225 is a maximum-strength probiotic for cases of acute gastrointestinal and immune challenges.